POSTER: Clinical validity of TTMV-HPV DNA liquid biopsies for the diagnosis and surveillance of HPV-associated oropharyngeal carcinoma

Scott A. Roof, Rocco Ferrandino, Sida Chen, Catharine Kappauf, Joshua Barlow, Brandon Gold, William Westra, Michael Berger, Marita S. Teng, Mohemmed N. Khan, Richard Lorne Bakst, Kunal K. Sindhu, Eric Michael Genden, Raymond L. Chai, Marshall R. Posner, and Krzysztof Misiukiewicz. J Clin Oncol. 2023. https://doi.org/10.1200/JCO.2023.41.16_suppl.6060

May 31, 2023


 

ABSTRACT: Circulating tumor HPV-DNA kinetics in p16+ oropharyngeal cancer patients undergoing adaptive radiation de-escalation based on mid-treatment nodal response

J.K. Kim, M. Tam, C. Oh, M. Feron-Rigodon, B. Joseph, A.E. Vaezi, Z. Li, T. Tran, G. Kim, E. Zan, P. Corby, C. Del Vecchio Fitz, J.D. Goldberg, T. Hochman, B. Givi, A. Jacobson, M. Persky, M. Persky, and K.S. Hu. International Journal of Radiation Oncology, Biology, Physics. 2022. https://doi.org/10.1016/j.ijrobp.2022.07.1385

November 1, 2022


 

ABSTRACT: ctHPVDNA and recurrence risk in MC1675, a secondary analysis of a phase III evaluation of de-escalated adjuvant radiation therapy (DART) vs. standard adjuvant treatment for HPV associated oropharyngeal squamous cell carcinoma

D.M. Routman, K. Van Abel, K.A. Price, S.H. Patel, M.L. Hinni, B. Fruth, S. Kumar, C. Del Vecchio Fitz, C. Kuperwasser, M.A. Neben-Wittich, L.A. McGee, S.C. Lester, D.L. Price, J.R. Janus, T.H. Nagel, A.V. Chintakuntlawar, P. Savvides, R.L. Foote, E.J. Moore, and D.J. Ma. International Journal of Radiation Oncology, Biology, Physics. 2022. https://doi.org/10.1016/j.ijrobp.2022.07.378

November 1, 2022


 

ABSTRACT: Association of plasma tumor tissue modified viral HPV DNA (TTMV) with tumor burden, treatment type, and outcome: A translational analysis from NRG-HN002

Sue S. Yom et al.  J Clin Oncol. 2022. https://doi.org/10.1200/JCO.2022.40.16_suppl.6006

June 3, 2022


 

ABSTRACT: Detection of plasma circulating tumor-tissue modified HPV DNA following trans-oral robotic surgery (TORS) and neck dissection for p16+ oropharyngeal squamous cell carcinoma

R.J.L. Maxwell, K. Poirier, K. Montone, S.D. Swisher-McClure, S. Kumar, C. Kuperwasser, J. Bauml, R. Cohen, J. Newman, R. Brody, K. Rajasekaran, A. Chalian, C. Rassekh, G.S. Weinstein, A. Lin, and J.N. Lukens. International Journal of Radiation Oncology, Biology, Physics. 2021. https://doi.org/10.1016/j.ijrobp.2021.07.1163.

November 1, 2021


 

ABSTRACT: Evaluating a clinically validated circulating tumor HPV DNA assay in saliva as a proximal biomarker in HPV+ oropharyngeal squamous cell carcinoma.

Sophie P. Gerndt, Ricardo J. Ramirez, Benjamin M. Wahle, Charlotte Kuperwasser, Alicia Gunning, Aadel A Chaudhuri, and Jose P. Zevallos. J Clin Oncol. 202. https://doi.org/10.1200/JCO.2021.39.15_suppl.6063

May 28, 2021