Resolving clinically indeterminate findings during anal cancer surveillance with TTMV-HPV DNA
Rafi Kabarriti, Shane Lloyd, James Jabalee, Laurie M. Gay, Tyler Slater, Kayleen Guzman, Corbin Jacobs, Sean Inocencio, Ray Lin, Cammie Nguyen, Iain MacEwan, Alexandra H. Crawford, Michael Rutenberg, Jaswinder Singh, Jennifer Ross, Sophia Kim-Wang, Chance Matthiesen, Kasha Neff, Gene-Fu Liu, Tiffany M. Juarez and Stanley L. Liauw. Cancers. 2026. https://doi.org/10.3390/cancers18010035
December 22, 2025
Evolving use of circulating tumor DNA for HPV+ oropharyngeal oarcinoma: Consensus recommendations from the California Head and Neck Consortium
Allen S. Ho, Justin T. Moyers, Shirin Attarian, Rupali Banker, Andrew Birkeland, Michelle M. Chen, Charles S. Coffey, Theresa Guo, Yarah Haidar, Jeremy P. Harris, F. Christopher Holsinger, Jared Inman, Julie K. Jang, Niels Kokot, Daniel Kwon, Andrew Larson, Alice Lin, Ellie Maghami, Jon Mallen-St. Clair, Abie Mendelsohn, Alain C. Mita, William R. Ryan, Maie St. John, Sagus Sampath, Kevin S. Scher, Uttam Sinha, Liyang Tang, Jacob Thomas, Tjoson Tjoa, Katherine C. Wai, Evan S. Walgama, Deborah J. Wong, Zachary S. Zumsteg
JCO Oncology Practice. 2025. https://ascopubs.org/doi/10.1200/OP-25-00450
December 4, 2025
Evaluating tumor tissue modified viral (TTMV)-HPV DNA for the early detection of anal squamous cell carcinoma recurrence
Rafi Kabarriti, Shane Lloyd, James Jabalee, Catherine Del Vecchio Fitz, Randa Tao, Tyler Slater, Corbin Jacobs, Sean Inocencio, Michael Rutenberg, Chance Matthiesen, Kasha Neff, Gene-Fu Liu, Tiffany M. Juarez and Stanley L. Liauw. Cancers. 2025. https://doi.org/10.3390/cancers17020174
January 8, 2025
Utility of circulating tumor tissue modified viral (TTMV)-HPV DNA to resolve clinically indeterminate findings in patients following definitive treatment for HPV-driven oropharyngeal cancer
Scott A. Roof, James Jabalee, Eleni M. Rettig, Susmita Chennareddy, Rocco M. Ferrandino, Sida Chen, Marshall R. Posner, Eric M. Genden, Raymond L. Chai, John Sims, Elaine Thrash, Scott J. Stern, Noah S. Kalman, Sreenija Yarlagadda, Adam Raben, Lydia Clements, Abie Mendelsohn, John M Kaczmar, Yadav Pandey, Mihir Bhayani, Catherine Del Vecchio Fitz, Glenn J. Hanna. Oral Oncol. 2024. http://doi.org/10.1016/j.oraloncology.2024.106874
June 14, 2024
Circulating tumor HPV DNA assessments after surgery for human papilloma virus-associated oropharynx carcinoma
Spenser S. Souza, Erika M. Stephens, Alexandra T. Bourdillon, Rohith Bhethanabotla, Zainab Farzal, Karolina Plonowska-Hirschfeld, Jesse R. Qualliotine, Chase M. Heaton, Patrick K. Ha, William R. Ryan. American Journal of Otolaryngology.
2024. https://doi.org/10.1016/j.amjoto.2023.104184.
March-April 2024
Preliminary results from retrospective correlation of circulating tumor DNA (ct-DNA) with imaging for HPV-positive oropharyngeal squamous cell carcinoma
Amit Agarwal, Alok A. Bhatt, Samip Patel, Girish Bathla, John Murray, Patricia Rhyner. American Journal of Neuroradiology. 2024. https://doi.org/10.3174/ajnr.A8242
March 12, 2024
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: Analysis of a phase II clinical trial and a cohort of long-term responders
Brandon M. Huffman, Harshabad Singh, Lestat R. Ali, Nora Horick, S. Jennifer Wang, Megan T. Hoffman, et al. Journal for ImmunoTherapy of Cancer. 2024. https://doi.org/10.1136/jitc-2023-008436
January 25, 2024
Circulating tumor-tissue modified HPV DNA testing in the clinical evaluation of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV study
Sana Batool, Rosh K.V. Sethi, Annette Wang, Kirsten Dabekaussen, Ann Marie Egloff, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Ravindra Uppaluri, Jennifer Shin, Eleni M. Rettig. Oral Oncology. 2023.
https://doi.org/10.1016/j.oraloncology.2023.106584.
October 12, 2023
Circulating tumor HPV DNA in patients with head and neck carcinoma: Correlation with HPV genotyping
Kevin Mijares, Rocco Ferrandino, Raymond Chai, Scott Roof, Swati Bhardwaj, Marshall Posner, and William H. Westra. The American Journal of Surgical Pathology. 2024. https://doi.org/10.1097/PAS.0000000000002134
September 27, 2023
From planned neck dissection to PET response to circulating tumour DNA: changes in post-treatment assessment of HPV-driven oropharyngeal cancer
Carl M. Post, Kim C. Ohaegbulam, and Timur Mitin. J Med Radiat Sci. 2024. https://doi.org/10.1002/jmrs.720
September 15, 2023
Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Glenn J. Hanna, Scott A. Roof, Jamie Jabalee, Eleni M. Rettig, Rocco Ferrandino, Sida Chen, Marshall R. Posner, Krzysztof J. Misiukiewicz, Eric M. Genden, Raymond L. Chai, John Sims, Elaine Thrash, Scott J. Stern, Noah S. Kalman, Sreenija Yarlagadda, Adam Raben, Lydia Clements, Abie Mendelsohn, John M. Kaczmar, Yadav Pandey, Mihir Bhayani, Piyush Gupta, Charlotte Kuperwasser, Catherine Del Vecchio Fitz, Barry M. Berger. Clin Cancer Res. 2023. https://doi.org/10.1158/1078-0432.CCR-23-1478
August 11, 2023
Performance of Liquid Biopsy for Diagnosis and Surveillance of Human Papillomavirus-Associated Oropharyngeal Cancer
Rocco M. Ferrandino, Sida Chen, Catharine Kappauf, et al. JAMA Otolaryngol Head Neck Surg. 2023. https://doi.org/10.1001/jamaoto.2023.1937
July 9, 2023
Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV16 DNA before head and neck cancer diagnosis
Eleni M. Rettig, Tim Waterboer, Edward Sim, Daniel L. Faden, Julia Butt, Glenn J. Hanna, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Herve Sroussi. Oral Oncology. 2023. https://doi.org/10.1016/j.oraloncology.2023.106417
May 4, 2023
Novel HPV associated oropharyngeal squamous cell carcinoma surveillance DNA assay cost analysis
Michael G. Lin, Alexander Zhu, Paul W. Read, Jonathan Garneau, and Christopher McLaughlin. The Laryngoscope. 2023. https://doi.org/10.1002/lary.30701
April 18, 2023
Circulating tumor HPV DNA as an alternative method to determine HPV status in oropharyngeal squamous cell carcinoma
Todd Lambert, Jason Tasoulas, Melissa Flores, Siddharth Sheth, and Samip N. Patel. Oral Oncology. 2023. https://doi.org/10.1016/j.oraloncology.2023.106361.
March 23, 2023
Analytical validation of NavDx, a cfDNA-based fragmentomic profiling assay for HPV-driven cancers
Alicia Gunning, Sunil Kumar, Cassin Kimmel Williams, Barry M. Berger, Stephen P. Naber, Piyush B. Gupta, Catherine Del Vecchio Fitz, and Charlotte Kuperwasser. Diagnostics. 2023. https://doi.org/10.3390/diagnostics13040725
February 14, 2023
Association of pretreatment circulating tumor tissue–modified viral HPV DNA with clinicopathologic factors in HPV-positive oropharyngeal cancer
Eleni M. Rettig, Annette A. Wang, Ngoc-Anh Tran, et al. JAMA Otolaryngol Head Neck Surg. 2022. https://doi.org/10.1001/jamaoto.2022.3282
October 27, 2022
Detection of occult recurrence using circulating tumor tissue modified viral HPV DNA among patients treated for HPV-driven oropharyngeal carcinoma
Barry M. Berger, Glenn J. Hanna, Marshall R. Posner, Eric M. Genden, Julio Lautersztain, Stephen P. Naber, Catherine Del Vecchio Fitz, and Charlotte Kuperwasser. Clin Cancer Res. 2022. https://doi.org/10.1158/1078-0432.CCR-22-0562.
May 16, 2022
Phase II multi-institutional clinical trial result of concurrent cetuximab and nivolumab in recurrent and/or metastatic head and neck squamous cell carcinoma
Christine H. Chung, Jiannong Li, Conor E. Steuer, Priyanka Bhateja, Matthew Johnson, Jude Masannat, Maria I. Poole, Feifei Song, Juan C. Hernandez-Prera, Helen Molina, Bruce M. Wenig, Sunil Kumar, Charlotte Kuperwasser, Philip J. Stephens, Joaquim M. Farinhas, Dong M. Shin, Julie A. Kish, Jameel Muzaffar, Kedar Kirtane, James W. Rocco, Michael J. Schell, Nabil F. Saba, Marcelo Bonomi. Clin Cancer Res. 2022. https://doi.org/10.1158/1078-0432.CCR-21-3849
March 28, 2022
Detection of circulating tumor human papillomavirus DNA before diagnosis of HPV-positive head and neck cancer
Eleni M. Rettig, Daniel L. Faden, Shaiba Sandhu, et al. Int J Cancer. 2022. https://doi.org/10.1002/ijc.33996
March 9, 2022
The economic impact of circulating tumor-tissue modified HPV DNA for the post-treatment surveillance of HPV-driven oropharyngeal cancer: A simulation☆
Matthew C. Ward, Jacob A. Miller, Gary V. Walker, Benjamin J. Moeller, Shlomo A. Koyfman, and Chirag Shah. Oral Oncology. 2022. https://doi.org/10.1016/j.oraloncology.2022.105721.
March 2022
Detectable postoperative circulating tumor human papillomavirus (HPV) DNA and association with recurrence in patients with HPV-associated oropharyngeal squamous cell carcinoma
David M. Routman, Sunil Kumar, Bisham S. Chera, Krishan R. Jethwa, Kathryn M. Van Abel, Kelsey Frechette, Todd DeWees, Michael Golafshar, Joaquin J. Garcia, Daniel L. Price, Jan L. Kasperbauer, Samil H. Patel, Michelle A. Neben-Wittich, Nadia L. Laack, Ashish V. Chintakuntlawar, Katharine A. Price, Minetta C. Liu, Robert L. Foote, Eric J. Moore, Gaorav P. Gupta, and Daniel J. Ma. International Journal of Radiation Oncology, Biology, Physics. 2022. https://doi.org/10.1016/j.ijrobp.2022.02.012
February 11, 2022
Estimated cost of circulating tumor DNA for posttreatment surveillance of human papillomavirus–associated oropharyngeal cancer
Roman O. Kowalchuk, Benjamin C. Kamdem Talom, Kathryn M. Van Abel, Daniel M. Ma, Mark R. Waddle, and David M. Routman. JAMA Netw Open. 2022. https://doi.org/10.1001/jamanetworkopen.2021.44783
January 25, 2022
Circulating tumor-tissue modified HPV DNA analysis for molecular disease monitoring after chemoradiation for anal squamous cell carcinoma: A case report
Stanley L. Liauw, Christina H. Son, Ardaman Shergill, and Benjamin D. Shogan. J Gastrointest Oncol. 2021. https://doi.org/10.21037/jgo-21-300
May 26, 2021
